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Amino acids, peptides and proteins in organic chemistry, Volume 4. Protection reactions, medicinal chemistry, combinatorial synthesis
Titre de série : Amino acids, peptides and proteins in organic chemistry, Volume 4 Titre : Protection reactions, medicinal chemistry, combinatorial synthesis Type de document : texte imprimé Auteurs : Andrew B. Hughes, Editeur scientifique Editeur : Weinheim : Wiley-VCH Année de publication : cop. 2011 Importance : 4 vol. (XX-531 p.) Présentation : formule, graph., couv. ill. en coul. Format : 25 cm ISBN/ISSN/EAN : 978-3-527-32103-2 Note générale : Éditeur : Wiley-VCH Verlag GmbH; Volume 4 édition (23 mai 2011)
Langue : : Anglais
Téléchargement : 552 pages
ISBN-10 : 3527631836
ISBN-13 : 978-3527631834Langues : Anglais (eng) Mots-clés : Protection reactions amino acid based peptidomimetics medicinal chemistry peptide drugs oral bioavailability asymmetic synthesis combinatorial synthesis Index. décimale : 547 Chimie Organique Résumé : This is the fourth of five books in the Amino Acids, Peptides and Proteins in Organic Synthesis series. Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international "who's who" in amino acid research, these volumes represent a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins. The practical value of each volume is heightened by the inclusion of experimental procedures. The 5 volumes cover the following topics: Volume 1: Origins and Synthesis of Amino Acids Volume 2: Modified Amino Acids, Organocatalysis and Enzymes Volume 3: Building Blocks, Catalysis and Coupling Chemistry Volume 4: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis Volume 5: Analysis and Function of Amino Acids and Peptides The fourth volume in this series is structured in three main sections. The first section is about protection reactions and amino acid based peptidomimetics. The second, and most extensive, part is devoted to the medicinal chemistry of amino acids. It includes, among others, the chemistry of alpha- and beta amino acids, peptide drugs, and advances in N- and O-glycopeptide synthesis. The final part deals with amino acids in combinatorial synthesis. Methods, such as phage display, library peptide synthesis, and computational design are described. Originally planned as a six volume series, Amino Acids, Peptides and Proteins in Organic Chemistry now completes with five volumes but remains comprehensive in both scope and coverage. Further information about the 5 Volume Set and purchasing details can be viewed here.
Biographie de l'auteur
Andrew Hughes is a reader and Head of the Department of Chemistry, La Trobe University, Melbourne, Australia. He obtained his degrees from the University of Western Australia. Post-doctoral appointments at the University of Cambridge starting 1989 included 3 years working with Professor Andrew Holmes before joining Professor Steven Ley's group in 1993. While at Cambridge he was appointed the Shell Research Fellow at Robinson College.Note de contenu : index Amino acids, peptides and proteins in organic chemistry, Volume 4. Protection reactions, medicinal chemistry, combinatorial synthesis [texte imprimé] / Andrew B. Hughes, Editeur scientifique . - Weinheim : Wiley-VCH, cop. 2011 . - 4 vol. (XX-531 p.) : formule, graph., couv. ill. en coul. ; 25 cm.
ISBN : 978-3-527-32103-2
Éditeur : Wiley-VCH Verlag GmbH; Volume 4 édition (23 mai 2011)
Langue : : Anglais
Téléchargement : 552 pages
ISBN-10 : 3527631836
ISBN-13 : 978-3527631834
Langues : Anglais (eng)
Mots-clés : Protection reactions amino acid based peptidomimetics medicinal chemistry peptide drugs oral bioavailability asymmetic synthesis combinatorial synthesis Index. décimale : 547 Chimie Organique Résumé : This is the fourth of five books in the Amino Acids, Peptides and Proteins in Organic Synthesis series. Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international "who's who" in amino acid research, these volumes represent a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins. The practical value of each volume is heightened by the inclusion of experimental procedures. The 5 volumes cover the following topics: Volume 1: Origins and Synthesis of Amino Acids Volume 2: Modified Amino Acids, Organocatalysis and Enzymes Volume 3: Building Blocks, Catalysis and Coupling Chemistry Volume 4: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis Volume 5: Analysis and Function of Amino Acids and Peptides The fourth volume in this series is structured in three main sections. The first section is about protection reactions and amino acid based peptidomimetics. The second, and most extensive, part is devoted to the medicinal chemistry of amino acids. It includes, among others, the chemistry of alpha- and beta amino acids, peptide drugs, and advances in N- and O-glycopeptide synthesis. The final part deals with amino acids in combinatorial synthesis. Methods, such as phage display, library peptide synthesis, and computational design are described. Originally planned as a six volume series, Amino Acids, Peptides and Proteins in Organic Chemistry now completes with five volumes but remains comprehensive in both scope and coverage. Further information about the 5 Volume Set and purchasing details can be viewed here.
Biographie de l'auteur
Andrew Hughes is a reader and Head of the Department of Chemistry, La Trobe University, Melbourne, Australia. He obtained his degrees from the University of Western Australia. Post-doctoral appointments at the University of Cambridge starting 1989 included 3 years working with Professor Andrew Holmes before joining Professor Steven Ley's group in 1993. While at Cambridge he was appointed the Shell Research Fellow at Robinson College.Note de contenu : index Exemplaires (1)
Code-barres Cote Support Localisation Section Disponibilité ST8561 547/166.1 Ouvrage Faculté des Sciences et de la Technologie 500 - Sciences de la nature et Mathématiques Exclu du prêt